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Conclusions This meta-analysis highlights the substantial and multidimensional clinical benefits of GLP-1 RAs therapy in individuals with overweight or obesity, with or without T2DM
Behavioral study also demonstrated that modulating AMPA/kainite, but not NMDA, receptor-mediated glutamatergic neurotransmission within VTA is involved in GLP-1-induced intake-suppressive effects (Mietlicki-Baase et al., 2013)
doi: 10.1002/1873-3468.12327 46 LouradourI.SharmaA.Morin-PoulardI.LetourneauM.VincentA.CrozatierM.et al
These typically normalize as the body adapts
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